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United States2026-03en

FY25 LDRD Project Accomplishments

Summary

This document reports accomplishments from FY25 LDRD projects conducted by Lawrence Livermore National Laboratory. One significant project addresses the challenge of developing rapid and affordable T-cell engineering to combat emerging pathogens and untreatable diseases. The approach involves delivering functional CAR proteins via nanodiscs, which has shown promising early results in accelerating the engineering process and reducing costs for personalized immune cell therapies.

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